The targeting construct inserted upstream of exon 12 a loxP site and downstream of exon 14 a loxP site, and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:130626)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count