CRISPR-targeting inserted into the 3 UTR a tetracycline response element (tetO), floxed stop cassette, myc- and flag-tagged mouse Cdkn1a coding sequence, woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability), and poly-A signal. (J:313419)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count