RMCE on KH2 cells replaced the FRT-flanked neo cassette with a cassette that contains a splice acceptor, polyadenylation sequence and the tetracycline promoter driving inducible expression of an HA-tagged cDNA for mouse Cdkn1a with the amino acid substitution of glycine with valine at position 12 followed by a polyadenylation sequence and hygromycin resistance cassette with an FRT site. (J:313419)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count