Using CRISPR/Cas9 endonuclease-mediated genome editing, a viral 2A oligopeptide sequence (T2A; mediates ribosomal skipping), an SV40 nuclear localization signal, and a Cre recombinase gene were inserted into the Agtr2 gene 3'UTR. (J:316137)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count