Guide RNAs (US1: GAGTCCCTCAGTGTGTGAGA and DS2: CAATGAGTCTGTACTGGAGC) and oligo donor DNAs are designed to introduce a 418 bp deletion downstream of exon 2, which includes the fms-intronic regulatory element (FIRE). (J:281171)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count