Guide RNAs (US1: GAGTCCCTCAGTGTGTGAGA and DS2: CAATGAGTCTGTACTGGAGC) and oligo donor DNAs are designed to introduce a 418 bp deletion downstream of exon 2, which includes the fms-intronic regulatory element (FIRE). (J:281171)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x CBA/J)F1
Endonuclease-mediated
Intragenic deletion
--
1
2
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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