Lysine codons 98 (AAA), 117 (AAG), 136 (AAG), 160 (AAG), and 161 (AAG) were changed to arginine (p.K98R + p.K117R + p.K136R + p.K160R + p.K161R). Cre-mediated recombination removed the loxP site flanked neomycin resistance gene cassette that was inserted into intron 4. (J:314680)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Nucleotide substitutions
--
1
65
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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