The targeting construct introduced a loxP site upstream of exon 2 and an FRT flanked neomycin resistance cassette with a 3' loxP site. Cre-mediated recombination removed the selection cassette. (J:314967)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count