A loxP site was inserted upstream of exon 4, and an FRT/loxP flanked neomycin selection cassette was inserted downstream of exon 7. The selection cassette was removed via Flp-mediated recombination leaving exons 4 to 7 floxed. (J:309372)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count