Using CRISPR/cas9 genome editing, guide RNAs (TACAAGTGGGAATTAATCTG and ACCCATCTTCTAGTTATGAA) and oligo donor DNAs are designed to introduce a loxP sites flanking exons 4a and 4b. (J:274377)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count