The mouse promoter from BAC clone 26630 was used to drive inducible icre expression in smooth muscle cells. An FRT-flanked beta-lactamase gene contained within the cre/ESR1 cassette was removed by flp mediated recombination. The transgene that originally integrated into Chr Y was found to to have translocated to Chr X in some female mice in the colony. The exact position is unknown. (J:248193)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
Spontaneous
Translocation
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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