Exon 4 was flanked by loxP sites. An FRT-flanked PGK-neomycin selection cassette was inserted upstream of exon 4 before the first lox site and was removed via Flp-mediated recombination. (J:315111)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count