The targeting construct inserted a loxP site upstream of Mir200b and an FRT-flanked neomycin resistance cassette with a 3 loxP site downstream of Mir429. Flp-mediated recombination removed the selection cassette and left the cluster floxed. (J:314874)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count