The targeting cassette inserted an FRT-flanked neomycin resistance cassette with a 5' loxP site upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. (J:296958)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count