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A transgene containing from 5' to 3', a loxP-flanked neo stop cassette, a rox-flanked stop cassette, and a 2A-NLS-ZsGreen and driven by the CAGGS promoter (chicken beta actin promoter with CMV enhancers) was inserted into intron 1. The mice with Gt(ROSA)26Sortm1(CAG-ZsGreen)Hamm were crossed with CAGGS Dre mice to remove the rox-flanked stop cassette. An intervening floxed neo-STOP cassette prevents expression of the ZsGreen except in the presence of cre when floxed neo-STOP cassette is excised. (J:314807)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
