A transgene containing from 5' to 3', a loxP-flanked neo stop cassette, a rox-flanked stop cassette, and a 2A-NLS-ZsGreen and driven by the CAGGS promoter (chicken beta actin promoter with CMV enhancers) was inserted into intron 1. An intervening floxed neo-STOP cassette and a rox-flanked stop cassette prevents expression of the ZsGreen except in the presence of cre and dre when both the floxed neo-STOP cassette and a rox-flanked stop cassette are excised. (J:314807)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top