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Using Red/ET recombination, the sequence encoding Dre recombinase together with a kanamycin/neomycin resistance cassette replaced the ATG start codon of the mouse Pomc gene of RP11-124K7 BAC clone. Five of seven transgenic lines showed similar specificity in the ARC and in the anterior and intermediate lobes of the pituitary. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:314806)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
