Using homologous recombination in ES cells, FRT flanked neo cassette and loxP was inserted upstream of the exons 5 of Plgrkt gene, and another loxP was inserted into intron downstream of the exon 7. The neo cassette was removed by crossing with FLP mice. (J:297274)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count