A loxP site was inserted upstream of exon 1. A floxed puromycin selection cassette was inserted downstream of exon 3. Cre-mediated recombination removed the selection cassette. (J:176174)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count