CRISPR-targeting introduced 400 codon optimized GA repeats directly downstream of the ATG start codon. An FRT site flanked neomycin-PGK selection cassette was inserted at the 3 end of the transgene. Flp-mediated recombination removed the neomycin-PGK cassette. (J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Endonuclease-mediated
Insertion
--
1
6
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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