CRISPR-targeting introduced 400 codon optimized GA repeats directly downstream of the ATG start codon. An FRT site flanked neomycin-PGK selection cassette was inserted at the 3 end of the transgene. Flp-mediated recombination removed the neomycin-PGK cassette. (J:82809)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count