A loxP site was inserted upstream of exon 1 and a loxP/FRT-flanked neomycin resistance cassette was inserted downstream of exon 1. Cre-mediated recombination removed the neomycin cassette and deleted exon 1 in the germline. (J:312384)
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A loxP site was inserted upstream of exon 1 and a loxP/FRT-flanked neomycin resistance cassette was inserted downstream of exon 1. Cre-mediated recombination removed the neomycin cassette and deleted exon 1 in the germline. (J:312384)