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Using homologous recombination in ES cells, the targeting vector inserted a single loxP into 5'UTR of the Sox4 gene, and a 3' loxP site followed by an frt-flanked neo cassette was inserted downstream of the single coding exon. The Neo cassette was removed by crossing to the Flp recombinase strain and deletion from the 3UTR was confirmed. (J:312333)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
