Using CRISPR/Cas9 technology, the cassette consisting of a floxed stop codon fused to mouse Fndc5 cDNA with polyadenylation signal and 2A-tdTomato, under the control of the CAG promoter was inserted into the intron1 of the Rosa26 locus. (J:312359)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count