Using homologous recombination in ES cells, a T2A-iCre sequence was inserted just before the Gck STOP signal in exon10, and an FRT-flanked positive selection marker puromycin was inserted in intron 8. (J:313162)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count