An IRES-creERT2 cassette followed by a polyA signal and a loxP-flanked neomycin cassette was inserted into the 3' UTR of the gene. Cre expression is induced in Lgr5 expressing cells by tamoxifen treatment. (J:194551)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count