Using homologous recombination in ES cells, LoxP sites flanking exon 36 of Plekho1 and neo cassette flanked by frt sites downstream of exon6 were inserted. The neo cassette was removed by crossing with flp deleter mice. (J:240968)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count