The transgene contains three copies of the antioxidant responsive element from the mouse Gsta1 promoter fused to a basal TK promoter driving inducible expression of human NRF2 (amino acids 1-433) with a FLAG-tagged luciferase reporter gene. Line M2 was generated. (J:257947)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count