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The targeting construct targetted into the locus a nuclear localized mKateV5 (nlsmKateV5) followed by a rabbit globin polyA sequence cloned between ROX recombination sites downstream of a CAGGS promoter. An FRT-pGK Neo-FRT cassette was also inserted in the construct, but it was removed by breeding mice to Flpe expressing mice. It is a fluorescent Dre-reporter allele in which upon execution of Roxed stop cassette, the fluorescent mKate can be visualized in the cells. (J:232545)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
