Log In|Sign Up
EN
The transgene consists of an 8.5-kb fragment of mouse Ins1 promoter (Ins1; nucleotides -8.5 kb to +12 bp relative to the transcriptional start site), a cDNA for rtTA, and a polyadenylation signal. Five lines (1-5) were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. Mouse Ins1 promoter shows high specificity in pancreatic betacells without leakage in the brain. (J:224637)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
