The Rosa-CAG targeting vector CAG-LSL-VSFP-Butterfly1.2-WPREbGHpA was inserted between exons 1 and 2 of the Gt(ROSA)26Sor locus. The targeting vector was designed with a floxed-STOP cassette (stop codons in all three reading frames linked to synthetic pA-hGHpA-PGKpA), the voltage-sensitive fluorescent protein Butterfly 1.2 coding sequence, a WPRE sequence (to enhance mRNA stability), a BGH polyA. It is a Cre-dependent reporter with a voltage indicator function. (J:219930)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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