The transgene contains the following elements: the mouse prion protein gene promoter and exon 1, intron 1 and exon 2, sequence coding for a FLAG tag in-frame with the human UBQLN2 cDNA, and Prnp exon 3 and downstream sequence. This allele expresses high levels of transgenic peptide. (J:267076)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count