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A LacZ reporter gene with the nuclear localization signal (NLS) followed by a polyadenylation sequence, was inserted into BAC clone RP23-78N21 with the 3' coverage of the Cdh6 locus that contains cis-regulatory modules for the somatosensory at the initiating ATG codon of the first coding exon of the Cdh6 gene. Eight founders were generated with similar expression patterns. Line 8 showing the highest level of CreERT2 protein expression in brain lysate was chosen for the studies. (J:205104)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
