A construct containing a CAG promoter driving expression of 2500002B13Rik replaced the beta-geo gene in the 2500002B13RikGt(Ayu21-T167)Imeg allele via recombinase mediated cassette exchange. Expression levels in the heart are elevated 40 times in heterozygous mice compared to wild-type controls. (J:311513)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count