Exons 3 and 4 were flanked by loxP sites and an FRT-flanked neomycin selection cassette was also inserted. The neomycin cassette was removed via Flp-mediated recombination, leaving exons 3-4 floxed. (J:311964)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count