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Targeting vector based on pKO scrambler V915 (Lexicon Genetics Inc., Woodland, TX) flanking a LoxP-pGK-Neo-LoxP selection cassette containing a BAC clone insertion containing intron 4, exon 5, and intron 5 of murine gene Pten (Gene ID 19211, NM 008960.2) with variant c.374A>G, p.Lys125Arg (K125R). (J:94077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
