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The transgene contains the following elements: the human CD68 promoter and intron 1, murine interleukin 3 signal peptide-coding sequence, in-frame with sequence coding for a FLAG tag, in-frame with the murine interleukin 10 cDNA without the signal peptide-coding sequence, and bovine growth hormone poly(A) signal sequence. An estimated 1-2 copies were inserted into the genome. (J:75579)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
