Tg(CD68-Il10)445Pmu

The transgene contains the following elements: the human CD68 promoter and intron 1, murine interleukin 3 signal peptide-coding sequence, in-frame with sequence coding for a FLAG tag, in-frame with the murine interleukin 10 cDNA without the signal peptide-coding sequence, and bovine growth hormone poly(A) signal sequence. An estimated 1-2 copies were inserted into the genome. (J:75579)