Hprt1^{tm4(KRT14-ROCK2*/ERT)Bicrq}

The targeting construct inserted upstream of exon 2 a Keratin 14 (KRT14) promoter, EGFP reporter gene, human ROCK2 (kinase-dead version) fused to an engineered version of the hormone binding domain of the estrogen receptor (ERT), and the wild-type promoter and exon one of the endogenous gene. (J:150868)