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The targeting vector is designed to replace exon 1 with a membrane-bound form of ovalbumin consisting of a fusion protein made up of the first 118 residues of the human transferrin receptor (which includes the cytoplasmic tail and signal/anchor domain) linked to residues 139-385 of the chicken ovalbumin gene (OVA), followed by a loxP-flanked neo cassette. Cre-mediated recombination removed the floxed neo cassette. (J:252604)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
