The targeting construct introduced an FRT flanked neomycin resistance cassette, and floxed exons 11 to 13. Flp-mediated recombination removed the selection cassette and left exons 11 through 13 floxed. (J:308863)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count