An FRT site, loxP site, neomycin cassette, FRT site, and second loxP site were inserted upstream of exon 3. A third loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neomycin cassette leaving exons 3-6 floxed. (J:311107)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count