The construct contains a 16 kilo-base-long Pitx2 mouse 129SV genomic fragment encompassing the Pitx2 promoter and 4.2 kb downstream of exon 6. A promotor-less CreERT2 cassette, including the CreERT2 coding sequence and a poly(A) tail, was cloned into the 5' region of Pitx2 exon 4. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:310646)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count