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EN
A T-to-G mutation was engineered in exon 2 to change serine codon 30 (TCT) to an alanine codon (GCT)(p.S30A), making that residue unphosphorylatable in the encoded peptide. The loxP site flanked neomycin resistance gene that was inserted into intron 1 was removed through subsequent cre-mediated recombination. (J:286257)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
