CRISPR/cas9 genome editing is used to create a 328 nt deletion resulting in complete loss of exon 3 (as well as 70bp upstream and 73bp downstream). Il2rg transcript Il2rg-201 was used as reference for the exon number and the guide sequences. (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count