A 2A-icre/ERT2 is introduced between the coding sequence of Slc17a7 Exon 12 and 3' UTR. Neo cassette flanked by frt sites was inserted within intron 11 to avoid disrupting poly(A) signal of Slc17a7. After homologous recombination in ES cells, the neo selection cassette was removed by Flp recombinase. (J:243876)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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