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The transgene was generated by a bacterial recombineering technique to insert a cre/ERT2 expression cassette containing the polyadenylation site (polyA) from the SV40 early region into the exon 1 of the mouse Zic2 gene of a BAC clone RP23-158G6 (CHORI). Two transgenic founder lines were selected and established. Line 1453 shows specific cre activity in the spinal cord. (J:284540)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
