This transgene contains the beta-globin promoter fragment fused to the 2.5 kb mouse Hoxa2 rhombomere 2-specific enhancer element to drive expression of cre in rhombomere 2. This transgene allele was made with the same construct used for the generation of Tg(Hbb/Hoxa2-cre)1Fmr. Two new founders were generated and selected to have a similar rhombomere 2-specific expression pattern as the previous transgenic line. One founder was used for the study. (J:309626)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count