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By using recombineering bacterial strain, the transgene with cre/ERT2 was inserted into a bacterial artificial chromosome (BAC: RP23 332E15) containing the mouse Lyve1 promoter and gene. Three strains transmitted the transgene in the germline after crossing with C57BL/6. Line 49 demonstrated the greatest and most reliable tdT induction efficiency and was used in all studies. (J:309509)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
