The following elements were inserted into exon 2 (where the endogenous start codon has been removed) of the Tau locus: a loxP site flanked STOP cassette, sequence for the rabies virus glycoprotein, IRES sequence, a nucleus-targeted lacZ gene, and poly(A) signal sequences. Only after cre-mediated removal of the STOP cassette will this allele express the rabies glycoprotein and lacZ genes. (J:306314)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
1
14
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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