The targeting construct inserted an IRES-Cre-pgk promoterdriven Flp recombination target (FRT)neomycin (neo)FRT cassette into final exon 11 of the Trpc5 gene by homologous recombination in ES cells. The FRT flanked neo selection cassette was removed by FLP-deleter mice. (J:287788)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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