In this construct, the tetO tetracycline responsive element (TRE) was placed between the modified d2EGFP reporter gene and the mouse sonic hedgehog cDNA. The two genes are arranged in opposite transcriptional orientation (head-to-head) and the SV40 poly(A) signal sequence was placed 3' of each. (J:306455)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count