The targeting construct replaced the coding sequence in exons 1 through 4 with a lacZ reporter gene and a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:309086)
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The targeting construct replaced the coding sequence in exons 1 through 4 with a lacZ reporter gene and a floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:309086)